Heterotopic ossification (HO) following amputation, musculoskeletal injuries, burns, deep surgeries, and trauma severely debilitates patients by restricting range of motion and causing pain. Burn injuries cost over $500 million annually and hip replacements cost over $5 billion dollars. Beyond these initial expenses, HO leads to hospital admissions and secondary operations incurring significant costs. Insights from related hyper-proliferative disorders such as fibrodysplasia ossificans progressiva (FOP) and explorations down associated pathways have uncovered agents in HO pathways.
Benjamin Levi, M.D.
Directed by Dr. Benjamin Levi, the Levi Lab and Center for Organogenesis & Trauma is located in the NL8 building on the UT Southwestern Medical Center campus. On the same floor, the laboratory offices for both Dr. Levi and lab members can be found in the corners of the research building. The 1500 sf state-of-the-art lab attends to an extensive scope and associated techniques and relies on invaluable, nearby resources such as:
Center of Excellence Scaling Leadership
Community Service Events
- VA Bingo
- Race Benefiting Food Gathers
- Ronald McDonald House
- Hope Clinic
- Orthopedic Surgery Laboratory
- UM Dental School
- Yuji Mishina lab
- Ernestina Schipani lab
- Kurt Hankenson Lab
- Center for Molecular Imaging
- Cederna laboratory
Rigor and Compliance
Dr. Levi appointed as Adjunct Associate Professor at Uniformed Services University (USUHS)
Dr. Levi awarded ACS Clowes Award
Charles Hwang, BS of Levi Lab awarded medical school Dean's Award for Research Excellence
Dr. Levi awarded AAS Plastic Surgery Young Investigator Award
Dr. Levi Awarded the ASBMR Fuller Albright Award
Dr. Levi awarded ASCI Young Investigator Award
Shawn Loder, BS of Levi Lab awarded medical school Dean's Award for Research Excellence
Dr. Levi awarded PSF Bernard G Sarnat Excellence in Grant Writing Award
Levi Laboratory awarded 2 new DOD Grants to tackle tendon injury and heterotopic ossification
Shailesh Agarwal, MD of the Levi Lab awarded Moses Gunn Crudap Award
Jonathan Peterson, BS of Levi Lab awarded medical school Dean's Award for Research Excellence
Dr. Levi awarded Joan L. and Julius H. Jacobson II Promising Investigator Award
Amy Strong, MD, PhD of the Levi Laboratory Awarded NIH Surgical Oncology T32 Award
Casey Kraft, BS of Levi Lab awarded medical school Graduation with Distinction in Research Award
Dr. Levi awarded American Association for the Surgery of Trauma Research & Education Foundation Scholarship
The Levi laboratory is proud to present a publication in the Journal of Clinical Investigation (JCI) Insights entitled “Macrophage TGF-β signaling...
The Levi laboratory in collaboration with the James laboratory is proud to present a publication in Bone Research (Nature) entitled...
The Levi laboratory is proud to present a publication in Nature Communications entitled "NGF-TrkA signaling dictates neural ingrowth and aberrant...
The Levi laboratory is proud to present a publication in Journal of Clinical Investigtation - Insights entitled “Contemporary perspectives on...
The Levi laboratory is proud to present a publication in Nature Communications entitled "Regulation of heterotopic ossification by monocytes in a...
Support Our Research
Burn/trauma and regenerative medicine researchers in plastic surgery seek to prevent the formation of bones in abnormal locations. Gifts help alleviate this condition affecting burn, auto accident, orthopaedic surgery and blast injury patients by providing additional resources to employ state of the art technologies, recruit talented researchers, and disseminate our scientific findings widely.